Impact of the Interactions of CYP2B6*6 and CYP2A6 Polymorphisms on the Treatment of Nicotine Dependence
نویسنده
چکیده
Submit Manuscript | http://medcraveonline.com Abbreviations: BGT: Behavioral Genetic Theory; CYP P-450: Cytochrome P450 Enzyme Genes; CO: Carbon Monoxide; FTND: Fagerström Test for Nicotine Dependence; GED: General Education Degree; NRT: Nicotine Replacement Therapy; SNPs: Single Nucleotides Polymorphisms; UW-TTURC: University of Wisconsin Transdisciplinary Tobacco Use Research Center; 3HC/ COT: 3’hydroxycotinine/cotinine; OR : Odd Ratio
منابع مشابه
CYP2A6 genetic polymorphism and its relation to risk of smoking dependence in male Iranians
Introduction: Nicotine is the psychoactive substance responsible for establishing and maintaining smoking dependence. CYP2A6 is the primary enzyme that inactivates nicotine to cotinine .Genetic variation in CYP2A6 accounts for some of the inter-individual variability in nicotine metabolism and has been indicated to influence smoking behavior and dependence. Therefore, the aim of this study was ...
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